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D-vitamin og solarier

Der forskes ihærdigt i sammenhængen mellem sol og sundhed, hvilket involverer emner som D-vitamin, kræft og humør. Herunder finder du henvisninger til en række relevante videnskabelige artikler, der er publiceret af anerkendte forskere i akademiske tidsskrifter. Listen er ikke en fuldstændig fortegnelse over forskningen på området, men blot et udpluk. Flere artikler kan findes ved at søge i forskningsdatabaser og på nettet.

Bemærk, at nedenstående er forskningsbaserede artikler skrevet af eksperter og derfor typisk skrevet på engelsk.

Der er ikke tale om populærvidenskabelige eller journalistiske artikler og heller ikke partsindlæg.

Tanning is associated with optimal vitamin D status (serum 25-hydroxyvitamin D concentration) and higher bone mineral density

Tidsskrift: American Journal of Clinical Nutrition

(Am J Clin Nutr 2004;80:1645–9)

December 2004

Forfattere: Vin Tangpricha, Adrian Turner, Catherine Spina, Sheila Decastro, Tai C. Chen og Michael F. Holick

Artiklen konkluderer, at brugen af et solarium, der udsender D-vitamin-producerende UV-stråling er forbundet med et højere niveau af D-vitamin.

Uddrag af tidsskriftets resumé: “Vitamin D is made in the skin on exposure to solar radiation, and it is necessary to optimal skeletal health. Subjects who use a tanning bed that emits ultravioletBradiation (290–315 nm) are likely to have higher 25-hydroxyvitamin D [25(OH)D] concentrations than do subjects who do not regularly use a tanning bed. […] Conclusion: The regular use of a tanning bed that emits vitamin D–producing ultraviolet radiation is associated with higher 25(OH)D concentrations and thus may have a benefit for the skeleton.”

Hele artiklen er tilgængelig her: http://www.ajcn.org/cgi/reprint/80/6/1645.pdf

Sun beds and cod liver oil as vitamin D sources

Tidsskrift: Journal of Photochemistry and Photobiology B: Biology

(J Photochem Photobiol B. 2008 May 29;91(2-3):125-31)

Maj 2008

Forfattere: Alina Carmen Porojnicu, Øyvind Sverre Bruland, Lage Aksnes, William B. Grant og Johan Moan

Denne artikel viser, at henholdsvis solarier og levertran bidrager til kroppens produktion af D-vitamin.

Uddrag af tidsskriftets resumé: “The objective of this study was to (1) to determine the contribution of moderate sun bed exposure to serum 25(OH)D3 [D-vitamin, red.] levels; (2) to estimate the decay time of a high 25(OH)D3 level obtained by sun bed exposure; and (3) to evaluate if the recommended ingestion of vitamin D is sufficient to maintain the 25(OH)D3 concentration obtained by sun bed exposure. […] Serum level of 25(OH)D3 increased by about 40% on the average.”

Læs tidsskriftets resumé her: http://www.ncbi.nlm.nih.gov/pubmed/18417354

Hele artiklen er tilgængelig her:http://www.bruland.info/PDF/2008/J%20Photobiol%20Vit%20D%20Sun%20Beds%20and%20Cod%20Liver%20Oil.pdf

Solar Radiation, Vitamin D and Cancer Incidence and Mortality in Norway

Tidsskrift: Anticancer research

(Anticancer Res 2009;29:3501-3509)

September 2009

Forfattere: Johan Moan, Arne Dahlback, Zoya Lagunova, Emanuela Cicarma og Alina Carmen Porojnicu

Denne artikel argumenterer for, at sol og D-vitamin produceret deraf samlet set giver en positiv effekt, der overstiger de kendte negative effekter.

Uddrag af tidsskriftets resumé: “Solar radiation is of fundamental importance for human development and health: On the one hand, too much of it can lead to skin ageing and skin cancer, whilst on the other, too little of it can result in vitamin D deficiency, and, thereby lead to high incidence and poor prognosis of internal cancer as well as a number of other diseases.”

Læs tidsskriftets resumé her: http://ar.iiarjournals.org/content/29/9/3501

Sunlight, vitamin D and the prevention of cancer: a systematic review of epidemiological studies

Tidsskrift: European Journal of Cancer Prevention

(Eur J Cancer Prev. 2009 Aug 26)

26. august 2009

Forfattere: Han Rhee, Jan Coebergh og Esther Vries

I en gennemgang af alle offentliggjorte studier af sammenhængen mellem kræft, sol og D-vitamin, konkluderer artiklen, at flere og flere beviser udpeger sol som en beskyttende faktor i forhold til flere type kræft.

Uddrag af tidsskriftets resumé: “The number of studies reporting beneficial effects of sunlight and vitamin D on several types of cancer with a high mortality rate is growing rapidly. Present health recommendations on sun exposure are mainly based on the increased risks for skin cancer. We reviewed all published studies concerning cancer and sun exposure and vitamin D, respectively, excluding those about skin cancer. […]We, therefore, conclude that there is accumulating evidence for sunlight as a protective factor for several types of cancer.”

Læs tidsskriftets resumé her: http://journals.lww.com/eurjcancerprev/Abstract/publishahead/Sunlight,_vitamin_D_and_the_prevention_of_cancer_.99966.aspx

On the epidemiology of influenza

Tidsskrift: Virology Journal

(Virol J. 2008 Feb 25;5:29)

25. februar 2008

Forfatter: John J. Cannell, Michael Zasloff, Cedric F. Garland, Robert Scragg og and Edward Giovannucci

Artiklen argumenterer for, at den udbredte mangel på D-vitamin er årsag til influenza-epidemier.

Uddrag af tidsskriftets resumé: “The epidemiology of influenza swarms with incongruities, incongruities exhaustively detailed by the late British epidemiologist, Edgar Hope-Simpson. He was the first to propose a parsimonious theory explaining why influenza is, as Gregg said, “seemingly unmindful of traditional infectious disease behavioral patterns.” Recent discoveries indicate vitamin D upregulates the endogenous antibiotics of innate immunity and suggest that the incongruities explored by Hope-Simpson may be secondary to the epidemiology of vitamin D deficiency. ”

Hele artiklen er tilgængelig her: http://www.virologyj.com/content/5/1/29

Does an active sun exposure habit lower the risk of venous thrombotic events? A D-lightful hypothesis

Tidsskrift: Journal of Thrombosis and Haemostasis

(J Thromb Haemost. 2009 Apr;7(4):605-10)

April 2009

Forfattere: Lindqvist, P.G.; Epstein, E. og Olsson, H.

Denne undersøgelse viser, at kvinder med aktive solvaner havde en reduceret risiko for at blive ramt af blodpropper.

Uddrag af tidsskriftets resumé: “Venous and arterial thrombotic complications [blodpropper, red.] exhibit a seasonal variation, with risk peaking in winter and dropping to a nadir in summer. We sought a possible correlation between sun exposure habits and venous thromboembolism (VTE) events. […] Women with more active sun exposure habits were at a significantly lower risk of VTE.”

Læs tidsskriftets resumé her: http://www.ingentaconnect.com/content/bsc/jth/2009/00000007/00000004/art00015

Sun and sun beds: inducers of vitamin D and skin cancer

Tidsskrift: Anticancer research

(Anticancer Res. 2009 Sep;29(9):3495-500)

September 2009

Forfattere: Emanuela Cicarma, Alina Carmen Porojnicu,  Zoya Lagunova, Arne Dahlback,  Asta Juzeniene og Johan Moan

Norsk forskning argumenterer for, at befolkninger i nordlige lande kan få en positiv effekt ud af at øge deres eksponering for UVB for at forbedre deres D-vitamin-niveau.

Uddrag af tidsskriftets resumé: “Solar radiation is both the main cause of all types of skin cancer, including cutaneous malignant melanoma (CMM), and the main source of vitamin D accompanied by its beneficial effects. The dilemma lies in that increased sun exposure could lead to an increase in skin cancers and yet is necessary for the better prognosis of internal cancers. […] Sun and sun beds act similarly: one quantum of radiation at a given wavelength has the same biological effect, irrespective of the source from which it comes. The winter levels of vitamin D are 10 to 100% lower than the summer levels in most populations, but can be brought up to summer levels by moderate sun bed exposure. Populations living at high latitudes would probably benefit from moderately increasing their exposure to UVB to provide a good vitamin D status.”

Læs tidsskriftets resumé her: http://www.ncbi.nlm.nih.gov/pubmed/19667143

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Holdninger

Sollys og solarium har samme virkning

Der er intet belæg for at påstå, at solarium skulle være mere skadeligt end sollys. Stigningen af tilfælde af hudkræft begyndte flere årtier før åbningen af det først solcenter.

Viden

Giver sol modermærkekræft?

Sol giver ikke modermærkekræft, mener professor emeritus, dermatolog og forsker Sam Shuster. I denne artikel fra British Medical Journal (27/7-2008) gennemgår han sine grunde. Der er en sikker forbindelse mellem sol og hudkræft − der typisk kan helbredes – men forbindelsen mellem sol og den farlige modermærkekræft højst usikker.

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